Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2228570
rs2228570
VDR
0.020 GeneticVariation BEFREE Our data suggest that donors' VDR rs2228570 AA alleles may play a major role in low serum 25(OH)D regarding pathological FLD in recipients after LDLT. 29750155

2018
dbSNP: rs2228570
rs2228570
VDR
0.020 GeneticVariation BEFREE Donor/recipient CYP27A1 rs4674344 and graft VDR rs2228570 may be related to low serum 25(OH)D and may play a major role in the development of fatty liver disease in recipients after living donor liver transplantation. 29935100

2018
dbSNP: rs58542926
rs58542926
TM6SF2
0.050 GeneticVariation BEFREE Decreased liver production/secretion of VLDL, decreased cholesterol and TGs in VLDL/LDL particles in serum, and increased tyrosine levels identify possible mechanisms by which rs58542926-T exerts its effects on increasing risk of fatty liver disease, decreasing cardiovascular disease, and increasing diabetes risk, respectively. 28539357

2017
dbSNP: rs58542926
rs58542926
TM6SF2
0.050 GeneticVariation BEFREE Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. 26457389

2016
dbSNP: rs58542926
rs58542926
TM6SF2
0.050 GeneticVariation BEFREE Carriers of the TM6SF2 E167K variant are more susceptible to progressive NASH, but are protected against cardiovascular disease. 25251399

2015
dbSNP: rs58542926
rs58542926
TM6SF2
0.050 GeneticVariation BEFREE Interestingly, patients harbouring the TM6SF2 rs58542926 T allele that predispose to NAFLD/NASH had higher LBP level. 28464257

2017
dbSNP: rs58542926
rs58542926
TM6SF2
0.050 GeneticVariation BEFREE Recently, genome-wide association studies led to the identification of the major inherited determinants of hepatic fat accumulation: patatin-like phospholipase domain-containing 3 (PNPLA3) I148M gene and transmembrane 6 superfamily member 2 (TM6SF2) E167K gene variants, involved in lipid droplets remodelling and very low-density lipoproteins secretion, are the major determinants of interindividual differences in liver steatosis, and susceptibility to progressive NASH. 26273621

2015
dbSNP: rs10499563
rs10499563
STEAP1B
0.010 GeneticVariation BEFREE The IL6 rs10499563 C allele was independently associated with the presence of definitive NASH, and increased ballooning and Mallory bodies. 27730688

2016
dbSNP: rs17107315
rs17107315
SPINK1
0.010 GeneticVariation BEFREE One subject with diffuse fatty liver disease and other with liver cirrhosis due to NAFLD had N34S mutation. 19502653

2009
dbSNP: rs4880
rs4880
SOD2
0.010 GeneticVariation BEFREE The anti-oxidative SOD2 47T>C genetic variant might increase susceptibility to NASH in Chinese. 24649902

2014
dbSNP: rs738491
rs738491
SAMM50 ; PNPLA3
0.710 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs738491
rs738491
SAMM50 ; PNPLA3
0.710 GeneticVariation BEFREE The rs12743824 and rs738491 SNPs were independently associated with FLD and steatohepatitis, respectively. 26352879

2015
dbSNP: rs1007863
rs1007863
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2073080
rs2073080
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2281292
rs2281292
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2401514
rs2401514
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs6006473
rs6006473
SAMM50 ; PARVB
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2073079
rs2073079
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2143571
rs2143571
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2235776
rs2235776
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2235777
rs2235777
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2235778
rs2235778
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2281298
rs2281298
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs2294922
rs2294922
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013
dbSNP: rs3761472
rs3761472
SAMM50
0.700 GeneticVariation GWASDB The ERLIN1-CHUK-CWF19L1 gene cluster influences liver fat deposition and hepatic inflammation in the NHLBI Family Heart Study. 23477746

2013